Stem Cells Coaxed Into Diabetes Treatment

Walk 22, 2004 — Some lab mice with diabetes now have ordinary blood sugar levels, much obliged to the wonder of stem cells. For people, this means a conceivable unused treatment for sort 1 diabetes.

The ponder, published in the diary Laboratory Examination, includes bone marrow cells, which are a source of stem cells — master cells that have the capacity to grow and develop into a assortment of cell sorts, including pancreas cells that deliver affront.

Type 1 diabetes creates when the insulin-producing cells of the pancreas are destroyed. Affront may be a hormone that moves glucose (a sugar) from the blood into the body’s cells, where it can be utilized for vitality or stored for later use.

In this study, stem cells were chemically coaxed in the research facility to gotten to be insulin-producing cells. The new insulin-producing cells were transplanted into mice that had sort 1 diabetes. The cells readily adapted to their environment and were able to deliver insulin and other hormones fundamental for typical blood sugar levels.

“We have shown that the control of bone marrow cells toward being capable of discharging affront may be finished with relative ease,” writes lead researcher Seh-Hoon Oh, PhD, with the University of Florida in Gainesville.

A stem cell can become an insulin-producing cell in fair 10 days, she adds, “thus giving an open cell source and a basic method for the cellular treatment of diabetes.

“Our comes about suggest that bone marrow cells may give researchers a capable apparatus in the consider of pancreatic [cell] development and function, as well as offering a modern potential instrument” for the treatment of type 1 diabetes, she composes.

SOURCE: Goodness, S. Laboratory Investigation online, Walk 22, 2004. WebMD Restorative Reference from Healthwise: “Sort 1 Diabetes.”

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